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Evgen Pharma gets green-light for trial of possible coronavirus treatment


Evgen Pharma PLC (LON:EVG) shares surged 11% higher to 13.75p in early trade on Friday after the group got the all-clear to start a trial of its SFX-01 lead candidate.

Evgen said all necessary regulatory approvals have now been received for the STAR trial, a Phase II/III trial to investigate whether SFX-01 can reduce the severity, or prevent the onset of, acute respiratory distress syndrome in patients with suspected coronavirus (COVID-19).

“We hope that the outcome of this trial will lead to an additional treatment for COVID-19 patients and that SFX-01 could play a big part in managing the current pandemic,” Huw Jones, the chief executive officer of Evgen said in a statement.

Sensyne Health PLC (LON:SENS) jumped 7.6% to 99.5p after it agreed to a research collaboration with US drugs giant, Bristol Myers Squibb.

The collaboration will see Sensyne deploy its artificial intelligence and machine learning technology to help better understand certain rare blood diseases.

Work will focus on Myeloproliferative Neoplasms to assess the progression of these blood cancers that are characterised by the over-production of white or red cells, or platelets.

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Sensyne Health PLC (LON:SENS) has agreed a research collaboration with Bristol Myers Squibb that will see it deploy its artificial intelligence and machine learning technology to help better understand certain rare blood diseases. Work will focus on Myeloproliferative Neoplasms to assess the progression of these blood cancers that are characterised by the over-production of white or red cells, or platelets. No financial terms were disclosed. This is Sensyne’s fourth partnership with a major pharma company following deals with Bayer, Roche and Alexion.

Braveheart Investment Group PLC (LON:BRH) has said a new antiviral face mask that can kill coronavirus (COVID-19) will go on sale by the end of the year. This follows a flurry of activity at Braveheart investee company Pharm2Farm (P2F), which has developed a textile coating incorporating nanoparticles with long-lasting virucidal properties. It now has testing results from two independent labs that show the mask textile has a ‘kill rate’ of over 90% for up to seven hours, meeting the requirements for ISO 18184 certification. Meanwhile, Braveheart’s sale of its 51.72% stake in P2F to Remote Monitored Systems PLC (LON:RMS) is expected to complete on November 5. As a result, Braveheart will own 37.12% of RMS.

Aminex PLC (LON:AEX) has announced the completion of its farm-out deal with ARA Petroleum Tanzania Limited (APT). “We are delighted to finally complete the farm-out and hand over operatorship of the Ruvuma PSA to APT,” said Robert Ambrose, Aminex chief executive in a statement. The company now retains a 25% interest in the Ruvuma asset – which includes the Ntorya gas project and exploration areas – and APT will fund a forward programme including the drilling of the Chikumbi-1 well and a new seismic programme over at least 200 square kilometres.

Avation PLC (LON:AVAP), the civil aircraft lessor, said it stayed in profit in its latest financial year in spite of the problems facing airlines due to coronavirus restrictions. Profits dropped 43% to US$14.3mln in the year to end June 2020, which was largely the result of US$35.5mln of impairment losses offset partially by an unrealised gain of US$27.1mln for purchase rights with plane manufacturer ATR. Revenue increased by 14% to US$135.3mln during the year, which was a new record said the company, and before the one-offs profits rose 28% to US$19.8mln.

Powerhouse Energy Group PLC (LON:PHE) has told investors that Dr Cameron Davies will retire as a director of the company on March 31, 2021. The company intends to appoint Mark Berry as a non-executive director. He is a partner in law firm Norton Rose Fulbright which has particular expertise in the energy industry, Powerhouse noted.

Shanta Gold Limited (LON:SHG) announced after the market close on Thursday that it is proposing to raise roughly £31mln by way of a placing and a direct subscription of shares priced at 16.5p each. All of the directors of the East Africa-focused gold producer, developer and explorer, have indicated an intention to participate in the subscription, up to an aggregate amount of about £270,000. The funds raised will pay for infill drilling, expansion drilling, technical studies and working capital over the next 36 months at the company’s West Kenya Project.

Pan African Resources plc (LON:PAF) has said its American depositary receipts (ADRs) are to be traded on the OTCQX Best Market, starting Friday, October 23, 2020. The OTCQX market is the highest tier of the over-the-counter (OTC) market operated by OTC Markets Group. The ADRs were previously traded on the Pink OTC market.

Power Metal Resources PLC (LON:POW) the AIM-listed metals exploration and development company said it has received notices to exercise warrants over 7,136,000 new ordinary shares of 0.1 pence each in the company. The warrant shares are being issued under the exercise for 4,636,000 warrants at an exercise price of 1.0p each and 2,500,000 warrants at an exercise price of 0.7p each. Subscription monies of £63,860 have been received by Power Metal in respect of these exercises.

Tiziana Life Sciences PLC (NASDAQ:TLSA) (LON:TILS), a biotechnology company focused on innovative therapeutics for oncology, inflammation and infectious diseases, said it has allotted and issued 285,714 ordinary shares of 3p each credited as fully paid at a price of 35p per share in respect of the exercise of 285,714 warrants held by a warrant holder.

Stobart Group PLC (LON:STOB), the aviation and energy infrastructure group, has said it will announce its interim results for the six months ended 31 August 2020 on Wednesday, November 4, 2020. The group will hold an investor presentation at 9.30am UK time on the same day hosted by Warwick Brady, its chief executive officer and Lewis Girdwood, its chief financial officer. The presentation will be hosted through the digital platform Investor Meet Company. Investors can access the webcast by visiting:

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